How does high-quality fetal bovine serum achieve endotoxin control ?

In the world of cell culture, there is a potential interfering factor that, although it does not directly "kill" the cells, can silently affect their growth state, differentiation ability and the reliability of experimental results - it is endotoxin.    Endotoxin, essentially a component of the cell wall of Gram-negative bacteria, has a significant biological activity effect on various cells, especially immune cells, stem cells and primary cells.

2026-01-07

The key to the success or failure of IVD raw material research and development: fetal bovine serum

With the rise of the IVD market, an increasing number of upstream raw material companies for IVD have also begun to increase their investment and production and development of IVD biological raw materials as their business volume grows. As a crucial link in the research and production of biological raw materials, the large-scale culture technology of mammalian cells has become an indispensable part of the research and production of IVD raw materials.

2025-10-27

Global Kang Bio / Why Doesn't fetal bovine Serum need heat inactivation?

In cell culture research, many researchers have a common confusion regarding the use of serum: whether or not to perform heat inactivation. Taking fetal bovine serum (FBS), which is hailed as the "golden nutrient source for cells", as an example, some laboratories still follow the traditional process of using a constant temperature of 56°C for 30 minutes to carry out "complement inactivation".

2025-10-10

History of Fetal Bovine Serum FBS use in cell culture

Ringer's cell culture-medium, developed by Sydney Ringer in 1882, was an early example of in vitro culture of animal tissue. In the following decades, driven by scientific and technological innovation, early animal cell culture and synthetic media have appeared. The 1940s saw the establishment of cell lines, the birth of basic media, and the development of protein-free media.

2025-01-07

How to judge the quality of Fetal Bovine Serum through COA

Fetal bovine serum is a serum obtained from bovine embryos and is commonly used to prepare animal cell culture media. Fetal bovine serum contains various growth factors and has low levels of antibodies.

2024-10-29

Contamination types, control and prevention of cell culture

In the process of cell culture, once contamination occurs, researchers usually face great challenges and losses. Cell contamination will not only cause delays in the progress of experiments, affect the output of research results, and may even pose a threat to other cell lines in the entire laboratory. Therefore, it is important to understand and master effective cell pollution treatment methods.

2024-08-01